Author Topic: FDA says restricting MRI contrast agents "not warranted"  (Read 6 times)

0 Members and 0 Guests are viewing this topic.

Offline agate

  • Administrator
  • *****
  • Posts: 7386
  • Location: Pacific Northwest
FDA says restricting MRI contrast agents "not warranted"
« on: May 24, 2017, 04:36:27 pm »
From NEJM Journal Watch, May 24, 2017:

Quote
FDA: Restricting MRI Contrast Agents "Not Warranted"

By Kristin J. Kelley

Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM

There isn't evidence to warrant restricting the use of gadolinium-based contrast agents (GBCAs), the IV drugs used during magnetic resonance imaging, the FDA has concluded.

The agency began evaluating the risk for adverse health events associated with the heavy metal gadolinium retained in the brain after multiple uses of GBCAs. Reports showed that while gadolinium is retained in the body (including the brain, bones, and skin), no adverse health effects were found to be associated with the retention, apart from a rare condition known as nephrogenic systemic fibrosis.

The safety of GBCAs will continue to be investigated by conducting more research, including studies on how gadolinium is retained in the body. Clinicians should follow the FDA recommendations issued in 2015.

FDA safety alert, May 22, 2017


NEJM Journal Watch (July 28, 2015), "MRI contrast agents linked to brain deposits"









SPMS, diagnosed 1980. Avonex 2001-2004. Copaxone 2007-2010.

Offline agate

  • Administrator
  • *****
  • Posts: 7386
  • Location: Pacific Northwest
A followup to this, in MedPage Today, July 1, 2017, "Gadolinium builds, even in normal brains":

https://www.medpagetoday.com/Neurology/MultipleSclerosis/66343?xid=nl_mpt_DHE_2017-06-30&eun=g345846d0r&pos=1





SPMS, diagnosed 1980. Avonex 2001-2004. Copaxone 2007-2010.

 

Related Topics

  Subject / Started by Replies Last post
2 Replies
51 Views
Last post March 17, 2017, 03:50:00 pm
by agate
0 Replies
9 Views
Last post December 09, 2016, 08:55:35 am
by agate
0 Replies
18 Views
Last post February 03, 2017, 01:26:23 pm
by agate
0 Replies
13 Views
Last post March 08, 2017, 02:47:14 pm
by agate
0 Replies
7 Views
Last post April 04, 2017, 03:06:55 pm
by agate