Author Topic: (Abst.) Bryostatin-1 alleviates experimental MS  (Read 77 times)

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Offline agate

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(Abst.) Bryostatin-1 alleviates experimental MS
« on: February 15, 2018, 09:34:57 am »
Abstract of "Bryostatin-1 alleviates experimental multiple sclerosis" by several Johns Hopkins researchers and published in PNAS (Proceedings of the National Academy of Sciences). From PubMed, February 15, 2018:


https://www.ncbi.nlm.nih.gov/pubmed/29440425


From the abstract:


Quote
More strikingly, bryo-1 reverses neurologic deficits after EAE onset, even when treatment is initiated at a late stage of disease when peak adaptive immunity has subsided.
And:

Quote
These findings suggest the potential for bryo-1 as a therapeutic agent in MS, particularly given its established clinical safety. Furthermore, the benefit of bryo-1, even in late treatment of EAE, combined with its targeting of innate myeloid cells suggests therapeutic potential in progressive forms of MS.

MS Speaks--online for 13 years

SPMS, diagnosed 1980. Avonex 2001-2004. Copaxone 2007-2010.

 

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