Author Topic: Excessive vitamin D dietary supplementation common in US  (Read 55 times)

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Offline agate

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Excessive vitamin D dietary supplementation common in US
« on: July 06, 2017, 02:43:26 pm »
There has been considerable evidence of a link between MS and vitamin D3 insufficiency--leading a number of persons with MS to increase their vitamin D3 intake by supplementing their diet with 5,000IU daily or even much more.  Some of the scientific researchers are raising questions about the zeal for taking vitamin D3 supplements in the US, though apparently they have not addressed themselves to the possible special needs for vitamin D3 among those with MS.

From NEJM Journal Watch, July 6, 2017:

Excessive Vitamin D Dietary Supplementation Is Common in the U.S.

Thomas L. Schwenk, MD reviewing Rooney MR et al. JAMA 2017 Jun 20.

Almost one fifth of adults took daily supplements ≥1000 IU, and 3% ingested ≥4000 IU.

Known and purported benefits of sufficient vitamin D have caused some patients to believe that taking doses higher than the recommended daily intake (600 IU for adults ≤70, and 800 IU for those >70) adds even more value. In this study, investigators used a national health and nutrition survey database to identify about 5000 participants for each 2-year cycle of dietary assessment (from 1999 to 2014), for a total of 39,243 participants (mean age, 47).

In the 20132014 survey, the prevalence of daily supplemental intake ≥1000 IU vitamin D was 18.2%, and prevalence of intake ≥4000 IU was 3.2%. High intake was most common in women (25.9%), non-Hispanic whites (21.8%), and older participants (age, ≥70; 38.5%). Intake of ≥1000 IU increased significantly from the 19992000 survey (0.3%) to the 20132014 survey.


Prior studies have suggested several risks associated with high-dose vitamin D, including excess fractures, falls, renal calculi, and all-cause mortality. The increasing prevalence of high supplement intake suggests that clinicians should be asking specifically about supplemental vitamin D use. In fact, as I was preparing this summary, a colleague mentioned that one of his patients was taking 5000 IU of vitamin D daily and had a very high 25-hydroxyvitamin D level (84 ng/mL); my colleague called her, discussed excessive use of vitamin D supplements, and sent her a copy of this JAMA study.

Rooney MR et al. Trends in use of high-dose vitamin D supplements exceeding 1000 or 4000 International Units daily, 19992014. JAMA 2017 Jun 20; 317:2448.

MS Speaks--online for 13 years

SPMS, diagnosed 1980. Avonex 2001-2004. Copaxone 2007-2010.


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