MS Speaks

Multiple Sclerosis => TREATMENTS => TYSABRI (natalizumab) => Topic started by: agate on June 12, 2014, 02:33:35 pm

Title: 462 PML cases as of 5/14--Tysabri considered safe beyond 2-3 years
Post by: agate on June 12, 2014, 02:33:35 pm

 An article in  Medscape Medical News, June 12, 2014, Natalizumab Continued Past 24 Months Safely in MS (http://www.medscape.com/viewarticle/826643#1), reports:

Quote

Between 2005 and May 2014, among 125,800 patients with MS treated in the postmarketing setting, 462 cases of PML have been reported, of which 23% were fatal, for an incidence of 3.6 cases/1000 treated. The highest prevalence has been in patients receiving natalizumab for 2 to 3 years.

The unofficial chefarztfrau Website lists 464 cases as of May 7.