I did a Google search for Ocrevus and your forum was one of the first pages of links Agate.
Well I started Ocrevus a week ago. I had the first half-dose. It went well, better than expected. My only reaction was a slight headache and that was likely from the steroids. They gave me a 250 mg drip, a long saline drip, extra strength Tylenol and 25 mg of Benadryl. I felt tired the first night when I got home but I kept drinking lots of water to help flush my system. The next day I felt wonderful from the steroids. I had no pains, lots of energy and a good mood. I got a lot of little jobs done around the house. The second day I was wiped out, sat around all day, tired as usual, and the third day all of my pain was back, business as usual.
Yesterday I had another good day like the day after the infusion. I even worked out in the yard for 90 minutes in the sun, heat, and humidity. I pulled lots of weeds and tended to the garden.
I get the second half dose next Wednesday, two weeks after the first. After that I'll be on the six month schedule. I'm really hopeful that this might even make me feel better.
I'm wondering if it has a whole body effect on inflammation when it wipes out the B cells. Because I've noticed an improvement in my IBS symptoms over that past few days.