Author Topic: 462 PML cases as of 5/14--Tysabri considered safe beyond 2-3 years  (Read 73 times)

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Offline agate

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 An article in  Medscape Medical News, June 12, 2014, Natalizumab Continued Past 24 Months Safely in MS, reports:

Quote
Between 2005 and May 2014, among 125,800 patients with MS treated in the postmarketing setting, 462 cases of PML have been reported, of which 23% were fatal, for an incidence of 3.6 cases/1000 treated. The highest prevalence has been in patients receiving natalizumab for 2 to 3 years.

The unofficial chefarztfrau Website lists 464 cases as of May 7.
MS Speaks--online for 12 years

SPMS, diagnosed 1980. Avonex 2001-2004. Copaxone 2007-2010.