HERE FOR 20 YEARS FOR PEOPLE WITH AN INTEREST IN MULTIPLE SCLEROSIS Skip to content

(Abst.) ANCA-associated life-threatening systemic vasculitis after alemtuzumab treatment for MS

434 Views 0 Replies

0 Members and 1 Guest are viewing this topic.

#1
From PubMed (February 23, 2020), "ANCA-associated life-threatening systemic vasculitis after alemtuzumab treatment for multiple sclerosis"


Alemtuzumab is highly effective in relapsing remitting multiple sclerosis (RRMS), but autoimmune adverse events are of concern. In contrast to rare cases of immune-mediated cutaneous vasculitis, sy...
PubMed · ncbi.nlm.nih.gov



ANCA vasculitis:


Quote
ANCA vasculitis is an autoimmune disease affecting small blood vessels in the body. It is caused by autoantibodies called ANCAs, or [/size]A[/color][/size]nti-[/color][/size]N[/color][/size]eutrophilic [/color][/size]C[/color][/size]ytoplasmic [/color][/size]A[/color][/size]utoantibodies. ANCAs target and attack a certain kind of white blood cells called neutrophils. They target a part of neutrophils called the cytoplasm (the inside of the cell.)[/color]


[from the UNC Kidney Center Website]
MS Speaks--online for 20 years

SPMS, diagnosed 1980. Avonex 2001-2004. Copaxone 2007-2010. Glatopa (glatiramer acetate 40mg 3 times/week)  12/16/20 - 3/16/24.