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Phase III trial: Ocrevus twice yearly w/10-minute subcutaneous injection

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#1
Maybe Ocrevus will be available as a twice-yearly 10-minute subcutaneous injection. It's not clear whether the injection can be self-administered but my guess is that the person with MS would need to go to a medical facility for the injection.


From Business Wire   (July 13, 2023)--"Positive Phase III results for Genetech's Ocrevus (ocrelizumab) twice a  year, 10-minute subcutaneous injection in patients with multiple sclerosis":
 

https://bit.ly/3DcjV7T
Last Edit: July 13, 2023, 09:55:03 am by agate
MS Speaks--online for 20 years

SPMS, diagnosed 1980. Avonex 2001-2004. Copaxone 2007-2010. Glatopa (glatiramer acetate 40mg 3 times/week)  12/16/20 - 3/16/24.
Positive results found for new Ocrevus subcutaneous formulation
Reply #1 on:
#2
This article makes it clear that the 10-minute subcutaneous version of Ocrevus isn't meant to be self-administered. The patient would go to an MS center for the injections, presumably.


From Multiple Sclerosis News Today (July 14, 2023)--"Positive results found for new Ocrevus under-the-skin formulation":


A new formulation of Ocrevus, given as a 10-minute under-the-skin injection, was found comparable to the approved version of the MS therapy.
Multiple Sclerosis News Today · multiplesclerosisnewstoday.com
MS Speaks--online for 20 years

SPMS, diagnosed 1980. Avonex 2001-2004. Copaxone 2007-2010. Glatopa (glatiramer acetate 40mg 3 times/week)  12/16/20 - 3/16/24.
#3
From Practical Neurology (July 23, 2023)--"Subcutaneous Ocrevus Similar to IV Treatment for Patients with PPMS or RMS":


Subcutaneous injection of Ocrevus (ocrelizumab; Genentech, South San Francisco, CA) was comparable to the intravenous (IV) infusion formulation of Ocrevus…
tinyurl.com
MS Speaks--online for 20 years

SPMS, diagnosed 1980. Avonex 2001-2004. Copaxone 2007-2010. Glatopa (glatiramer acetate 40mg 3 times/week)  12/16/20 - 3/16/24.
(ECTRIMS) New under-the-skin Ocrevus found effective in MS
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#4
From Multiple Sclerosis News Today (October 12, 2023)--"ECTRIMS 2023: New under-the-skin Ocrevus found effective in MS":


Most MS patients treated with a new under-the-skin formulation of Ocrevus had no relapses or new MRI activity over six months, data show.
Multiple Sclerosis News Today · bit.ly
MS Speaks--online for 20 years

SPMS, diagnosed 1980. Avonex 2001-2004. Copaxone 2007-2010. Glatopa (glatiramer acetate 40mg 3 times/week)  12/16/20 - 3/16/24.