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Non-approved (off-label) treatments used for MS disease modification

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#1
Cellcept (mycophonolate mofetil), Cladribine, Cytoxan (cyclophosphamide), Imuran (Azothioprine), Minocycline, Rituxan (rituximab), and statins are drugs that are prescribed off-label for MS.

The National MS Society lists them, with brief descriptions, and this list seems important enough to become a "sticky" thread, always near the top of the page:

"Non-approved treatments used for MS disease modification".
MS Speaks--online for 20 years

SPMS, diagnosed 1980. Avonex 2001-2004. Copaxone 2007-2010. Glatopa (glatiramer acetate 40mg 3 times/week)  12/16/20 - 3/16/24.
#2
From PubMed (August 16, 2018) this abstract of an article by researchers at Beth Israel Deaconess Medical Center in Boston  has the title "Anti-JC virus antibody index changes in rituximab-treated MS patients":


Rituximab, a monoclonal antibody to CD20, is an effective treatment for relapsing remitting multiple sclerosis (MS) reducing relapse rate by at least 50% over time. Although the mechanism for this ...
PubMed · ncbi.nlm.nih.gov
MS Speaks--online for 20 years

SPMS, diagnosed 1980. Avonex 2001-2004. Copaxone 2007-2010. Glatopa (glatiramer acetate 40mg 3 times/week)  12/16/20 - 3/16/24.