MS Speaks

From PubMed (December 22, 2025)--"The effect of dietary interventions on peripheral markers of inflammation among people with multiple sclerosis:  A systematic review and meta-analysis of randomized controlled trials":


https://pubmed.ncbi.nlm.nih.gov/41422672/


This University of Iowa study includes among its authors Dr. Terry Wahls, whose controversial Wahls Protocol may have been among the dietary interventions involved in this study. Interestingly, it looks as if her diet (which is a modified paleo diet) seems not to have shown any effect on peripheral markers of inflammation:

Seven assessed dietary effects on C-reactive protein (CRP), with five showing reductions, particularly in Mediterranean, plant-based, and calorie-restricted diets, and two showing no between-group differences.

Also, the Conflict of Interest Statement at the end of the abstract reveals that none of the authors except Dr. Wahls has any conflicts to disclose but Dr. Wahls has a surprisingly long list of them.

Festivus, the holiday for the rest of us according to a "Seinfeld" episode, is observed December 23.




FESTIVUS GREETINGS TO EVERYONE!

From PubMed (December 20, 2025)--"Managing reactivation of multiple sclerosis during treatment with natalizumab":


https://pubmed.ncbi.nlm.nih.gov/41420376/

From PubMed (December 18, 2025)--"Efficacy of caffeine supplementation on fatigue in patients with multiple sclerosis:  A randomized double-blind placebo-controlled trial"


https://pubmed.ncbi.nlm.nih.gov/41406935/


I was interested in this because I routinely consume about as much caffeine daily as these patients were being given.  Diet Coke contains slightly more caffeine than Diet Pepsi, FWIW.